Altered CD226/TIGIT expressions were associated with activated NK phenotypes in primary anti-phospholipid syndrome and affected by IL-4/JAK pathway

Conclusion: Our data revealed significant imbalanced CD226/TIGIT expressions on NK cells in pAPS, which closely associated with activated NK subsets phenotypes and more complicated autoantibody status. CD226/TIGIT imbalanced may be affected by IL-4/JAK pathway activation.PMID:38386917 | DOI:10.1093/cei/uxae016

Source: Clinical and Developmental Immunology - February 22, 2024 Category: Allergy & Immunology Authors: Yan Long Ke-Jia Lu Chang-Sheng Xia Jing-Hong Feng Wen-Yi Li Yin-Ting Ma Yuan-Yuan Sun Chun-Hong Fan Chun Li Source Type: research