What lessons are learned? our changing practice during thirty years of hereditary angioedema treatment

Hereditary angioedema (HAE) is a rare genetic disorder (1:50,000 – 100,000 in the US) characterized by unpredictable and recurrent episodes of swelling without hives in different parts of the body1. Generally, it is caused by a deficiency or a loss of function of C1 esterase inhibitor (C1 INH) due to a mutation in SERPING11. HAE can lead to significant morbidit y including death due to laryngeal swelling and asphyxia1, 2. There is a limited number of published case series. We are here reporting some lessons learned from our 30-year experience with our HAE patient population.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research