Modulation of intestinal metabolites by calorie restriction and its association with gut microbiota in a xenograft model of colorectal cancer

ConclusionCalorie restriction affects the abundance of gut microbes such asNitrospirae phylum andLactobacillus genus in mouse model of colorectal cancer, leading to changes in the metabolites such as D-Proline 、Isoleucyl-Valine, which contributes to the suppression of in vivo growth of CRC by calorie restriction.
Source: Hormones and Cancer - Category: Cancer & Oncology Source Type: research