Analytical performances of a point-of-care loop-mediated isothermal amplification (LAMP) assay to detect Group B Streptococcus in intrapartum pregnant women living in the Democratic Republic of the Congo

Infection is an important cause of maternal, foetal, and infant mortality in resource-constrained settings [1]. Children living in sub-Saharan Africa are ten-fold more likely to die at and/or around birth compared to high-income countries [2]. Worldwide, Streptococcus agalactiae, commonly referred to as Group B Streptococcus (GBS), is the leading infectious cause of stillbirth, and neonatal morbidity and mortality [3,4]. GBS colonizes the gastrointestinal and/or genital tract of 15% to 40% of healthy adults, the rectum being the reservoir [5].
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research