Analytical performances of a point-of-care loop-mediated isothermal amplification (LAMP) assay to detect Group B Streptococcus in intrapartum pregnant women living in the Democratic Republic of the Congo
Infection is an important cause of maternal, foetal, and infant mortality in resource-constrained settings [1]. Children living in sub-Saharan Africa are ten-fold more likely to die at and/or around birth compared to high-income countries [2]. Worldwide, Streptococcus agalactiae, commonly referred to as Group B Streptococcus (GBS), is the leading infectious cause of stillbirth, and neonatal morbidity and mortality [3,4]. GBS colonizes the gastrointestinal and/or genital tract of 15% to 40% of healthy adults, the rectum being the reservoir [5].
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Serge Tonen-Wolyec, Noel Labana Otuli, Monde Otsatre-Okuti, Raelle Atenyi-Kasemire, Raphael Dupont, Laurent B élec Source Type: research
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