Bortezomib modulated the autophagy-lysosomal pathway in a TFEB-dependent manner in multiple myeloma

CONCLUSION: Bortezomib effectively inhibits MM cell proliferation and induces autophagy, partly through TFEB-mediated mechanisms, with potential involvement of the MAPK pathway.PMID:38368721 | DOI:10.1016/j.leukres.2024.107455

Source: Cell Research - February 18, 2024 Category: Cytology Authors: Rongjuan Zhang Xinhong Yang Xiaomin Shi Enhong Xing Lihong Wang Changlai Hao Zhihua Zhang Source Type: research