Alzheimer's Disease-Related Psychosis is Positively Correlated with Preserved Hippocampal Volume

Psychosis presents as delusions and/or hallucinations, and occurs in approximately 41% of Alzheimer's disease (AD) patients, leading to accelerated decline in cognitive function. Alzheimer's disease is characterized by the presence of overall brain cortical atrophy, which is most notable in association areas and the limbic system, including the hippocampus. However, associations between neuroanatomical changes in AD and AD-related psychosis are not well studied, in particular as they relate to APOE4, which may play a stronger modulatory role in females when compared to males.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Poster # EI7 Source Type: research