SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/mTOR Signaling Pathways

CONCLUSION: SSPH I inhibited EMT, migration, and invasion of NSCLC cells by suppressing MAPK/ERK1/2 and PI3K/AKT/mTOR signaling pathways, suggesting that the natural compound SSPH I could be used for inhibiting metastasis of NSCLC.PMID:38305308 | DOI:10.2174/0115748928283132240103073039

Source: Recent Patents on Anti-Cancer Drug Discovery - February 2, 2024 Category: Cancer & Oncology Authors: Jinling Zhou Jian Luo Rizhi Gan Limin Zhi Huan Zhou Meixian Lv Yinmei Huang Gang Liang Source Type: research