METTL3-mediated m < sup > 6 < /sup > A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition

In conclusion, our research demonstrates that METTL3-mediated m6A modification of SOX4 plays a crucial role in regulating osteoblast proliferation and differentiation through its recognition by YTHDF3. Our research confirms METTL3-m6A-SOX4-YTHDF3 as an essential axis and potential mechanism in OP.PMID:38195035 | DOI:10.1016/j.cellsig.2024.111038

Source: Cellular Signalling - January 9, 2024 Category: Cytology Authors: Zhi-Wei Feng Bo Peng Sheng-Hong Wang Da-Cheng Zhao Yao-Bin Wang Ao Yang Hong-Wei Zhan Xiao-Yun Sheng Li-Hu Xu Xiao-Jun Ren Fei Yang Bin Geng Ya-Yi Xia Source Type: research