New Iridoids and Acyclic Monoterpenoids from the Roots and Rhizomes of Valeriana officinalis var. latifolia

Chem Biodivers. 2024 Feb 7:e202301949. doi: 10.1002/cbdv.202301949. Online ahead of print.ABSTRACTFive new iridoids, valeralides A-E (1-5), two new acyclic monoterpenoids, valeralides F (6) and G (7), together with two known iridoids (8 and 9), were isolated from the roots and rhizomes of Valeriana officinalis var. latifolia. Their structures were elucidated based on 1D and 2D NMR, as well as HR-ESI-MS spectroscopic data. The absolute configuration of compounds 1-4 were elucidated based on electronic circular dichroism (ECD) calculation. In addition, all the isolates were evaluated for their inhibition on nitric oxide production, cytotoxicity and anti-influenza A virus activity.PMID:38326086 | DOI:10.1002/cbdv.202301949
Source: Chemistry and Biodiversity - Category: Biochemistry Authors: Source Type: research