Inhibition of Taurine-upregulated Gene 1 Upregulates MiR-34a-5p to Protect against Myocardial Ischemia/Reperfusion via Autophagy Regulation

CONCLUSION: These findings indicated that inhibiting TUG1 may reduce the extent of myocardial I/R injury by regulating miR-34a-5p. Taken together, these results suggest that LncRNA TUG1 may represent a novel therapeutic target for myocardial I/R injury.PMID:38299288 | DOI:10.2174/0113862073267559231106074309

Source: Combinatorial Chemistry and High Throughput Screening - February 1, 2024 Category: Chemistry Authors: Qunjun Duan Aiqiang Dong Haifeng Cheng Shufen Zhang Wei Chen Weijun Yang Source Type: research