Inclusion of deuterated glycopeptides provides increased sequence coverage in hydrogen/deuterium exchange mass spectrometry analysis of SARS-CoV-2 spike glycoprotein

CONCLUSION: Inclusion of deuterated glycopeptides improves the analysis of the conformational dynamics of glycoproteins such as viral surface antigens and cellular receptors.PMID:38355883 | DOI:10.1002/rcm.9690

Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Christopher A Haynes Theodore R Keppel Betlehem Mekonnen Sarah H Osman Yu Zhou Adrian R Woolfitt Jakub Baudys John R Barr Dongxia Wang Source Type: research