Applying the Fragility Index to Randomized Controlled Trials Evaluating Total Neoadjuvant Therapy for Rectal Cancer: A Methodological Survey

CONCLUSIONS: The robustness of outcomes from trials assessing TNT for LARC was found to be questionable. Most outcomes were fragile, as determined by the FI. This survey is limited by the number of included studies.PMID:38341094 | DOI:10.1016/j.radonc.2024.110148

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 10, 2024 Category: Radiology Authors: Tyler McKechnie Kelly Brennan Cagla Eskicioglu Ameer Farooq Sunil Patel Source Type: research