Type I acquired cutis laxa: Report of a unique progressive case and short review

We present the case of a 30-year-old man diagnosed with type I ACL with progressive systemic involvement at the renal, pulmonary, and digestive levels. Histological analysis of the skin revealed reduction and fragmentation of elastic fibers. Immunosuppressive treatment was started with prednisone, cyclophosphamide, and rituximab, with which a complete response to proteinuria was achieved and the progression of lung damage was limited. Autoimmune, infectious, and neoplastic diseases were ruled out.PMID:38278360 | DOI:10.1016/j.amjms.2024.01.015
Source: The American Journal of the Medical Sciences - Category: General Medicine Authors: Source Type: research