Phenotyping of COPD with MRI in comparison to same-day CT in a multi-centre trial

ConclusionConcordance of MRI and CT for phenotyping of COPD in a multi-centre setting was substantial with variable inter-modality and inter-reader concordance for single diagnostic key features.Clinical relevance statementMRI of lung morphology may well serve as a radiation-free imaging modality for COPD in scientific and clinical settings, given that its potential and limitations as shown here are carefully considered.Key Points• In a multi-centre setting, MRI and CT showed substantial concordance for phenotyping of COPD (airway-/emphysema-/mixed-type).• Individual features of COPD demonstrated variable inter-modality concordance with features of pulmonary hypertension showing the highest and bronchiectasis showing the lowest concordance.• For all single features of COPD, inter-reader agreement was lower on MRI than on CT.
Source: European Radiology - Category: Radiology Source Type: research