The Evolution of Guidelines for the Evaluation and Management of Urinary Tract Infections in Children: Can We Finally Agree?

Disorders of the kidneys were recognized in China (2500-3000 BC) with recommendations for the analysis of the pulse and urine and treatment with myrrh, herbs and acupuncture. The ancient Greeks described signs and symptoms of UTIs. Galen (Rome, 2nd Century) described UTIs associated with obstruction. There was little advancement in diagnosis or management for the next 1300 years until the 19th century brought recognition of the germ theory of disease. Highly toxic non-specific agents were used for treatment until the introduction of sulfanilamide in 1937.
Source: Journal of Pediatric Urology - Category: Urology & Nephrology Authors: Source Type: research