A role of NR4A2 in Graves ’ disease: regulation of Th17/Treg

ConclusionThese results indicate that the low level of NR4A2 in GD patients may suppress Treg differentiation, but have no influence on Th17 differentiation, leading to the imbalance of Th17/Treg and contributing to the development of GD. Revealing the role of NR4A2 in GD provides a novel insight for the treatment of GD.
Source: Endocrine - Category: Endocrinology Source Type: research