A novel, small anti-HBV compound reduces HBsAg and HBV-DNA by destabilizing HBV-RNA

ConclusionsWe have identified SAG-524 as novel and orally bioavailable HBV-RNA destabilizers which can reduce HBsAg and HBV-DNA levels, and possibly contribute a functional cure.Graphical Abstract

http://link.springer.com/10.1007/s00535-023-02070-y

Source: Journal of Gastroenterology - February 5, 2024 Category: Gastroenterology Source Type: research