Regulation of CARD8 Expression by ANRIL and Association of CARD8 Single Nucleotide Polymorphism rs2043211 (p.C10X) With Ischemic Stroke [Clinical Sciences]

Conclusions—
CARD8 is a downstream target gene regulated by ANRIL. Single nucleotide polymorphism rs2043211 in CARD8 is significantly associated with ischemic stroke. ANRIL may increase the risk of ischemic stroke through regulation of the CARD8 pathway.

Source: Stroke - January 27, 2014 Category: Neurology Authors: Bai, Y., Nie, S., Jiang, G., Zhou, Y., Zhou, M., Zhao, Y., Li, S., Wang, F., Lv, Q., Huang, Y., Yang, Q., Li, Q., Li, Y., Xia, Y., Liu, Y., Liu, J., Qian, J., Li, B., Wu, G., Wu, Y., Wang, B., Cheng, X., Yang, Y., Ke, T., Li, H., Ren, X., Ma, X., Liao, Y. Tags: Functional genomics, Genetics of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research