Distinct metabolomic profiles are associated with changes over time and sustained unresponsiveness in children on peanut oral immunotherapy

Prior studies of food allergy have identified metabolomic pathways involved in immune function and allergy that are associated with having food allergies, but there is limited data around oral immunotherapy (OIT), desensitization, and immune tolerance. We aim to characterize metabolomic changes during desensitization through OIT.

Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Jennifer Styles, Sarita Patil, Bert Ruiter, Neal Smith, Clary Clish, Jessica Lasky-Su, Wayne Shreffler, Yamini Virkud Source Type: research