Characteristics of extra-oral halitosis induced by functional constipation: a prospective cohort study

Characteristics of extra-oral halitosis induced by functional constipation (FC) have never been revealed. To address this, this prospective cohort was conducted with 100 FC patients, who were divided into a halitosis group and a negative group. Organoleptic score (OLS) ⩾ 2 in nose breath was diagnosed as extra-oral halitosis. Concentration of overall volatile sulfur compounds (VSCs) measured by Halimeter, concentration of hydrogen sulfide (HS), methanethiol (MT), dimethyl sulfide (DMS) and their total amount measured by OralChroma in nose breath was recorded as C-VSC, C-HS, C-MT, C-DMS and C-sum respectively. We found that 82% (82/100) of the FC patients had extra-oral halitosis. However, only 12.5% (3/82) and 1.22% (1/82) of halitosis group were correctly diagnosed with the current diagnostic threshold of C-VSC ⩾ 110 parts per billion (ppb) and ⩾150 p pb. C-VSC, C-DMS and C-sum were significantly higher in the halitosis group compared to the negative group (all P
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Source Type: research