Endometrial transcriptome profiling of patients with recurrent implantation failure during hormone replacement therapy cycles

ConclusionOur study shows that ER-related genes share similar gene expression patterns during WOI in both natural and HRT cycles, and their aberrant expression is associated with WOI displacements. The improvement of pregnancy outcomes in RIF patients by adjusting ET timing according to ERD results demonstrates the importance of transcriptome-based endometrial receptivity assessment and the clinical efficiency of ERD model.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research