Advancements in Therapeutic Development: Kidney Organoids and Organs-on-a-Chip

The use of animal models in therapeutic development has long been the standard practice. However, ethical concerns and the inherent species differences have prompted a reevaluation of the experimental approach in human disease studies. The urgent need for alternative model systems that better mimic human pathophysiology has led to the emergence of organoids, innovative in vitro models, to simulate human organs in vitro. These organoids have gained widespread acceptance in disease models, and drug development research.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: mini review Source Type: research