Non-Cirrhotic Portal Hypertension: an Overview

AbstractPurpose of ReviewNon-cirrhotic portal hypertension (NCPH) is a broad term, which includes a heterogeneous group of disorders characterized by elevated portal pressure in the absence of cirrhosis. Despite a better understanding, the diagnosis and treatment remains challenging. This review gives new insights into some of the recent advances.Recent FindingsAlthough current guidelines for varices screening/surveillance are inadequate for NCPH, discovery of new genetic mutations helps us better understand its pathogenesis. Endohepatology is a promising emerging technique for an accurate diagnosis of NCPH. Pregnancy is not contraindicated however; multidisciplinary team approach is needed for an optimal outcome.
Source: Current Hepatitis Reports - Category: Infectious Diseases Source Type: research