Eliciting and stop dose during oral food challenges for peanut and common tree nuts in different age groups

ConclusionsTwo third of children under 6 years of age successfully consumed all the provided doses during OFCs with a negative outcome. The eliciting dose for objective symptoms was not associated with age, and in a substantial number of OFCs with positive outcome, symptoms occurred after eating the final dose. These findings suggest that in case of an uneventful OFC, the outcome should be drawn only after a cumulative dose of 4.4  g has been consumed to avoid the risk of a potential false negative outcome.

Source: Immunity, Inflammation and Disease - January 19, 2024 Category: Allergy & Immunology Authors: Wouter W. de Weger, Diede Jansen, Lidy van Lente, Gerbrich N. van der Meulen, Arvid W. A. Kamps Tags: ORIGINAL ARTICLE Source Type: research