Autoantibody-Mediated Depletion of IL-1RA in Still ’s Disease and Potential Impact of IL-1 Targeting Therapies

ConclusionAutoantibodies neutralizing IL-1Ra may represent a novel patho-mechanism in a subgroup of Still ’s disease patients, which is sensitive to high-dose IL-1 blocking therapy.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research