The Efficacy of Tradipitant in Patients with Diabetic and Idiopathic Gastroparesis in Phase III Randomized Placebo-Controlled Clinical Trial

Neurokinin receptor 1 (NK1R) antagonists are effective in reducing nausea and vomiting in chemo-therapy induced emesis. We investigated the safety and efficacy of tradipitant, an NK1R antagonist, in patients with idiopathic and diabetic gastroparesis.

Source: Clinical Gastroenterology and Hepatology - January 16, 2024 Category: Gastroenterology Authors: Jesse L. Carlin, Christos Polymeropoulos, Michael Camilleri, Anthony Lembo, Michaela Fisher, Caleigh Kupersmith, Darby Madonick, Paula Moszczynski, Sandra Smieszek, Changfu Xiao, Gunther Birznieks, Mihael H. Polymeropoulos Source Type: research