Effects of an intraoperative intravenous Bolus Dose of Dexmedetomidine on postoperative catheter-related bladder discomfort in male patients undergoing transurethral resection of bladder tumors: a randomized, double-blind, controlled trial

ConclusionThe effect of intravenous bolus doses of dexmedetomidine on postoperative CRBD was dose-independent, whereas intravenous administration of 0.5  µg/kg dexmedetomidine reduced the early postoperative incidence of CRBD with minimal side effects.Trial registrationClinical trial number and registry URL: ChiCTR 2,000,034,657,http://www.chictr.org.cn, date of registration: July 14, 2020.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research