Hydraulic resistance of three-dimensional pial perivascular spaces in the brain

ConclusionsNeglecting off-axis velocity components underestimates the average resistance, but the error can be reduced with a simple correction factor. These results could increase the accuracy of future models of brain-wide and local CSF flow, enabling better prediction of clearance, for example, as it varies with age, brain state, and pathological conditions.
Source: Fluids and Barriers of the CNS - Category: Neuroscience Source Type: research