Does Age Influence Gastrointestinal Status Responses to Exertional-heat Stress?
Int J Sports Med DOI: 10.1055/a-2195-3131This meta-data exploration aimed to determine the impact of exertional-heat
stress (EHS) on gastrointestinal status of masters age and young adult endurance
athletes. Sixteen MASTERS (mean: 44y) and twenty-one YOUNG (26y) recreational
endurance athletes completed 2 h of running at 60%
˙V O2max in 35˚C ambient
conditions. Blood samples were collected pre-, immediately and 1 h post-EHS, and
analyzed for markers of exercise-induced gastrointestinal syndrome (EIGS).
Thermo-physiological measures and gastrointestinal symptoms (GIS) were recorded
every 10–20 min during EHS. Peak Δ pre- to post-EHS did not
substantially differ (p>0.05) between MASTERS and YOUNG for intestinal
epithelial injury [I-FABP: 1652pg/ml vs. 1524pg/ml,
respectively], bacterial endotoxic translocation [sCD14:
-0.09µg/mL vs. 0.84µg/mL, respectively],
lipopolysaccharide-binding protein [LBP: 0.26µg/mL vs.
1.76µg/mL, respectively], and systemic inflammatory response
profile (SIR-Profile: 92.0arb.unit vs. 154arb.unit, respectively). A
significantly higher peak Δ pre- to post-EHS in endogenous endotoxin
anti-body IgM (p=0.042), and pro-inflammatory cytokine IL-1β
(p=0.038), was observed in YOUNG compared to MASTERS. No difference was
observed between incidence (81% and ...
Source: International Journal of Sports Medicine - Category: Sports Medicine Authors: Young, Pascale Henningsen, Kayla Snipe, Rhiannon Gaskell, Stephanie Alcock, Rebekah Mika, Alice Rauch, Christopher Costa, Ricardo J. S. Tags: Physiology & Biochemistry Source Type: research