Sentinel Lymph Node Biopsy Calculators for Informed Decision-Making

National Comprehensive Cancer Network (NCCN) guidelines recommend sentinel node biopsy (SNB) for patients with melanomas at least 1 mm in depth; however, selecting low-risk patients remains challenging. Models incorporating multiple clinical and pathologic variables associated with tumor aggressiveness (such as mitotic index and ulceration) may enable more reliable selection of low-risk patients to safely avoid SNB or benefit from SNB. Two models have been developed to assist in this decision-making process, from Memorial Sloan Kettering Cancer Center (MSKCC) and from the Melanoma Institute of Australia (MIA).
Source: JAMA Surgery - Category: Sports Medicine Source Type: research