Heterogeneous Nuclear Ribonucleoprotein F Deficiency in Mouse Podocyte Promotes Podocytopathy Mediated by Methyltransferase-like 14 Nuclear Translocation Resulting in Sirtuin-1 Gene Inhibition
Conclusion: HnRNP F deficiency in podocytes promotes podocytopathy through activation of Mettl14 expression and its nuclear translocation to inhibit Sirt1 expression, underscoring the protective role of HnRNP F against podocyte injury.PMID:38195017 | DOI:10.1016/j.trsl.2024.01.002
Source: Translational Research : the journal of laboratory and clinical medicine - Category: Laboratory Medicine Authors: Min-Chun Liao Chao-Sheng Lo Yu-Chao Pang Wen-Xia Yang Ke Su Xin-Ping Zhao Kana N Miyata Junzheng Peng Julie R Ingelfinger John S D Chan Shao-Ling Zhang Source Type: research
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