Abnormal variation and prognostic significance of circulating immune cells in patients with nasopharyngeal carcinoma treated with chemoradiotherapy: a prospective cohort study

CONCLUSIONS: The disproportion of circulating immune cells was observed in patients with NPC before treatment. CRT further aggravated immune dysfunction. Notably, a lower percentage of CD19+ B cells and EBV DNA-positive status before treatment were independent predictors of a worse prognosis. Thus, the measurement of circulating immune cells may help elucidate immune function status and predict the outcomes of patients with NPC.PMID:38192995 | PMC:PMC10774047 | DOI:10.21037/tcr-23-2024

Source: Cancer Control - January 9, 2024 Category: Cancer & Oncology Authors: Chaoxiong Huang Jianming Ding Chuanzhong Huang Ligen Yu Imjai Chitapanarux Michael Benedict A Mejia Zhaodong Fei Chuanben Chen Source Type: research