An immune gene expression risk score for distant metastases after radiotherapy for cervical cancer

CONCLUSION: The immune metastatic risk score addresses important challenges in the treatment of cervical cancer - identifying patients at high risk of DM after radiotherapy. The findings of this study indicate that high tumor mutational burden and a 'cold', immune-excluded tumor microenvironment influence distant metastatic recurrence. Further validation of the risk score is needed.PMID:38180733 | DOI:10.1158/1078-0432.CCR-23-2085

Source: Clinical Cancer Research - January 5, 2024 Category: Cancer & Oncology Authors: Jelena Lukovic Melania Pintilie Kathy Han Anthony W Fyles Jeff P Bruce Rene Quevedo Trevor J Pugh Christina S Fjeldbo Heidi Lyng Michael F Milosevic Source Type: research