Effects of Codeine on Esophageal Peristalsis in Patients With Ineffective Esophageal Motility: Studies Using High-resolution Manometry

CONCLUSIONS: In IEM patients, acute administration of codeine increases contraction vigor and reduces distal latency of primary esophageal peristalsis, but has no effect on secondary peristalsis. Future studies are required to further elucidate clinical relevance of these findings, especially in the setting of gastroesophageal reflux disease with IEM.PMID:38173157 | DOI:10.5056/jnm22131

Source: Journal of Neurogastroenterology and Motility - January 4, 2024 Category: Gastroenterology Authors: Wei-Yi Lei Tso-Tsai Liu Wei-Chuan Chang Chih-Hsun Yi Jui-Sheng Hung Ming-Wun Wong Shu-Wei Liang Lin Lin Chien-Lin Chen Source Type: research