The association between activation of the ERK1/2-NF- κB signaling pathway by TIMP2 expression and chronic renal allograft dysfunction in the CRAD rat model

CONCLUSION: A decrease of TIMP2 can alleviate the progression of inflammation in CRAD via inhibition of the ERK1/2-NF-κB signaling pathway.PMID:38184210 | DOI:10.1016/j.trim.2023.101984

Source: Transplant Immunology - January 6, 2024 Category: Transplant Surgery Authors: Tong Chen Shiquan Wu Ling Feng Siyu Long Yu Liu Caibin Zhang Wenqian Lu Yuli Shen Shanshan Jiang Wenya Chen Guoai Hong Li Zhou Fang Wang Yuechan Luo Hequn Zou Source Type: research