Preparation and characterizations of antibacterial iodine-containing coatings on pure Ti

J Mech Behav Biomed Mater. 2024 Jan 1;151:106366. doi: 10.1016/j.jmbbm.2023.106366. Online ahead of print.ABSTRACTIodine-containing coatings were prepared on pure Ti surfaces via electrochemical deposition to enhance their antibacterial properties. The factors influencing iodine content were analyzed using an orthogonal experiment. The electrochemically deposited samples were characterized using scanning electron microscopy with energy dispersive spectroscopy and X-ray photoelectron spectroscopy, and their antibacterial properties and cytotoxicity were evaluated. The results showed that changing the deposition time is an effective way to control the iodine content. The iodine content, coating thickness, and adhesion of the samples increased with deposition time. Iodine in the coatings mainly exists in three forms, which are I2, I3-, and pentavalent iodine. For samples with iodine-containing coatings, the antibacterial ratios against E. coli and S. aureus were greater than 90% and increased with increasing iodine content. Although the samples with iodine-containing coatings showed some inhibition of the proliferation of MC3T3-E1 cells, the cell viabilities were all higher than 80%, suggesting that iodine-containing coatings are biosafe.PMID:38176198 | DOI:10.1016/j.jmbbm.2023.106366
Source: Journal of the Mechanical Behavior of Biomedical Materials - Category: Materials Science Authors: Source Type: research