The effect of calcium hydroxide pastes on isolated vital nerve fibers
Extrusion of medicaments during root canal treatment may result in injury to the surrounding periapical tissues1,2. One of the materials used for root canal disinfection is calcium hydroxide (Ca(OH)2). Its use dates back to the 1920s, proving effective for disinfection, hard tissue stimulation, and apical closure of immature teeth with necrotic pulps3. The biological actions of Ca(OH)2 are based on the ionic dissociation of its Ca2+ and OH- ions. The release of hydroxyl ions (OH-) creates an alkaline environment that is antibacterial and promotes hard tissue stimulation3,4.
Source: Journal of Endodontics - Category: Dentistry Authors: Dwight D. Rice, Anupama Grandhi, Gina Delia Roque-Torres, Udochukwu Oyoyo, Leif K. Bakland Tags: Basic Research-Biology Source Type: research