Neonatal hypoglycemia and neurodevelopmental outcomes: Yesterday, today, tomorrow

Conclusion:  To adequately define if a more permissive approach is risk-free for neurodevelopmental outcomes, more research on continuous glucose monitoring and long-term follow-up is still needed.What is Known:• Neonatal hypoglycemia (NH) is a well-known cause of brain injury that could be prevented to avoid  neurodevelopmental impairment.• Diagnosis is challenging, considering the different suggested operational thresholds for NH (<36,<40,<45,<47  or<50 mg/dl).What is New:• A 36 mg/dl threshold seems to be not associated with a worse psychomotor development at 18 months of life  when compared to the “traditional” threshold (47 mg/dl).• Further studies on long-term neurodevelopmental outcomes are required before suggesting a more permissive  management of NH.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research