Nicotinamide prevention in diabetes-induced alterations in the rat liver

Conclusions. NAm counteracts diabetes-induced impairments in the rat liver through improvement of its detoxifying function, partial restoration of oxidative stress, NAD+ level, normalization of redox state of free cytosolic NAD+/NADH-couples, and prevention of PARP-1 cleavage.PMID:38127690 | DOI:10.2478/enr-2023-0031

Source: Endocrine Regulations - December 21, 2023 Category: Endocrinology Authors: Tamara Kuchmerovska Lesya Yanitska Oksana Horkunenko Mykhailo Guzyk Tetiana Tykhonenko Irina Pryvrotska Source Type: research