ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban

CONCLUSIONS: These data point to ZBTB20 act as a fine-tuning modulator of PLN expression and SERCA2a activity, thereby offering new perspective on the regulation of basal contractility in the mammalian heart.PMID:38166470 | DOI:10.1161/CIRCRESAHA.123.323798

Source: Circulation Research - January 3, 2024 Category: Cardiology Authors: An-Jing Ren Chunchun Wei Ya-Jin Liu Mengna Liu Ping Wang Juan Fan Kai Wang Sha Zhang Zhenbang Qin Qiu-Xiao Ren Yanjun Zheng Yu-Xia Chen Zhifang Xie Ling Gao Yi Zhu Youyi Zhang Huang-Tian Yang Weiping J Zhang Source Type: research