Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer ’s disease

Triggering receptor expressed on myeloid cells 2 (TREM2) plays a critical role in microglial activation, survival, and apoptosis, as well as in Alzheimer ’s disease (AD) pathogenesis. We previously reported the MS...

Source: Molecular Neurodegeneration - January 3, 2024 Category: Neurology Authors: Lihua Wang, Niko-Petteri Nyk änen, Daniel Western, Priyanka Gorijala, Jigyasha Timsina, Fuhai Li, Zhaohua Wang, Muhammad Ali, Chengran Yang, Menghan Liu, William Brock, Marta Marquié, Mercè Boada, Ignacio Alvarez, Miquel Aguilar, Pau Pastor & hellip; Tags: Research article Source Type: research