Deciphering the roles of subcellular distribution and interactions involving the MEF2 binding region, the ankyrin repeat binding motif and the catalytic site of HDAC4 in Drosophila neuronal morphogenesis

Dysregulation of nucleocytoplasmic shuttling of histone deacetylase 4 (HDAC4) is associated with several neurodevelopmental and neurodegenerative disorders. Consequently, understanding the roles of nuclear and...

Source: BMC Biology - January 2, 2024 Category: Biology Authors: Wei Jun Tan, Hannah R. Hawley, Sarah J. Wilson and Helen L. Fitzsimons Tags: Research article Source Type: research