OTUD1 promotes hypertensive kidney fibrosis and injury by deubiquitinating CDK9 in renal epithelial cells

This study demonstrates that OTUD1 mediates HRD by targeting CDK9 in kidney epithelial cells, suggesting OTUD1 is a potential target in treating this disease.PMID:38110583 | DOI:10.1038/s41401-023-01192-6

Source: Acta Pharmacologica Sinica - December 19, 2023 Category: Drugs & Pharmacology Authors: Meng-Yang Wang Tian-Xiang Yu Qin-Yan Wang Xue Han Xiang Hu Shi-Ju Ye Xiao-Hong Long Yi Wang Hong Zhu Wu Luo Guang Liang Source Type: research