The potential use of ascorbic acid to recover the cellular senescence of lipopolysaccharide-induced human apical papilla cells: an in vitro study

ConclusionsLPS significantly promoted cellular senescence on hAPCs and diminished the cell function capacity. Co-presence of ascorbic acid could impede cellular senescence and possibly improve the regenerative capacity of LPS-induced senescent hAPCsin vitro.Clinical relevanceThe data support thein vitro potential benefit of ascorbic acid on cellular senescence recovery of apical papilla cells.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research