Expert commentary for: Late adult-onset Niemann Pick type C (NPC): An “atypical” typical presentation at the age of 62

In a recently Movement Disorders Rounds, Dr. Mario Sousa and colleagues describe a challenging case of a late onset Niemann Pick Type C (NPC) disease [1]. The patient was a 67-year-old woman that started at the age of 62 with a progressive gait and balance disorder, cognitive impairment and speech affection. Summarizing main findings in neurological examination the patient presented a vertical supra-nuclear gaze palsy (VSGP) in combination with a mild cerebellar ataxia, slight slowness without decreasing of amplitude in finger tapping test, absence of rigidity and a wide based gait.
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research