The role of α-synuclein in exocytosis

Exp Neurol. 2023 Dec 24:114668. doi: 10.1016/j.expneurol.2023.114668. Online ahead of print.ABSTRACTThe pathogenesis of degeneration in Parkinson's disease (PD) remains poorly understood but multiple lines of evidence have converged on the presynaptic protein α-synuclein (αsyn). αSyn has been shown to regulate several cellular processes, however, its normal function remains poorly understood. In this review, we will specifically focus on its role in exocytosis.PMID:38147972 | DOI:10.1016/j.expneurol.2023.114668
Source: Experimental Neurology - Category: Neurology Authors: Source Type: research