Purging myeloma cell contaminants and simultaneous expansion of peripheral blood mobilised stem cells

HSCs are vital tissue stem cells responsible for producing all hematopoietic cells throughout a person's lifetime [1]. HSCs harvested from the body are essential medical resources for HSCT, which can be classified into two types: allogeneic HSCT and autologous HSCT [2]. These procedures are primarily performed for patients with hematological malignancies after chemotherapy. Commonly, PBSCs are used for autologous HSCT as the donor cell source for patients with multiple myeloma or malignant lymphoma [3,4], but this poses several challenges.
Source: Experimental Hematology - Category: Hematology Authors: Tags: Article Source Type: research