Rapid-release reversible bonding of PMMA-based microfluidic devices with PBMA coating

In this study, a new approach is proposed for the reversible bonding of PMMA-based microfluidics, a layer of PBMA (with a very similar structure to PMMA) was coated on the surface of PMMA and then use the thermal fusion method to achieve the bonding with a high bonding strength, a tensile bonding strength of around 0.8 MPa was achieved. For debond process, a rapid temperature drop will trigger the immediate release of the bonding within several seconds. Detailed bonding strength measurement and biocompatibility tests were also conducted in this study. The proposed bonding method could have wide application potential in the fabrication of PMMA-based microfluidics.PMID:38141082 | DOI:10.1007/s10544-023-00690-y
Source: Biomedical Microdevices - Category: Biomedical Engineering Authors: Source Type: research