The Brain's Response to Reward Anticipation and Depression in Adolescence: Dimensionality, Specificity, and Longitudinal Predictions in a Community-Based Sample.

CONCLUSIONS: The findings suggest that reduced striatal activation operates as a mechanism across the risk spectrum for depression. It is associated with anhedonia in healthy adolescents and is a behavioral indicator of positive valence systems, consistent with predictions based on the Research Domain Criteria.
PMID: 26085042 [PubMed - as supplied by publisher]

Source: The American Journal of Psychiatry - June 18, 2015 Category: Psychiatry Authors: Stringaris A, Vidal-Ribas Belil P, Artiges E, Lemaitre H, Gollier-Briant F, Wolke S, Vulser H, Miranda R, Penttilä J, Struve M, Fadai T, Kappel V, Grimmer Y, Goodman R, Poustka L, Conrod P, Cattrell A, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Flo Tags: Am J Psychiatry Source Type: research