Ferrostatin-1 improves neurological impairment induced by ischemia/reperfusion injury in the spinal cord through ERK1/2/SP1/GPX4

In conclusion, our results indicate that Fer-1 inhibited ferroptosis in spinal cord anterior horn neurons, improving neurological impairment and BSCB damage after SCIRI through the ERK1/2/SP1/GPX4 signaling pathway in rats.PMID:38141803 | DOI:10.1016/j.expneurol.2023.114659

Source: Experimental Neurology - December 23, 2023 Category: Neurology Authors: Sidan Liu Fengshou Chen Jie Han Limei Wang Yan Dong Source Type: research